python subplot space between plots

fig.subplots_adjust(hspace=.5)

import matplotlib.pyplot as plt

fig, axes = plt.subplots(nrows=4, ncols=4)
fig.tight_layout() # Or equivalently,  "plt.tight_layout()"

plt.show()

import matplotlib.pyplot as plt

fig, axes = plt.subplots(nrows=4, ncols=4)
fig.tight_layout(rect=[0, 0.03, 1, 0.95]) # Or equivalently, "plt.tight_layout()"

plt.show()